| Customization: | Available |
|---|---|
| Certification: | RoHS, BRC, ISO, FDA, HACCP |
| Assay Method: | HPLC |
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[ Product Name ] Senna Extract 8% Sennosides (A+B)
[ Botanical Source ] Senna alexandrina Mill.
[ Appearance ] Brown yellow powder
[ Part Used ] Leaf
[ Active Ingredients ] 8% Sennosides (A+B)
[ Shelf Life ] 2 years if sealed and store away from direct sun light.
[ Introduction ]
Senna leaf extract is extracted from the dried leaflets of senna. Its taste is sweet and bitter, and it has a good effect of diuresis, laxative, heat release and stagnation. It is often used clinically to treat heat stagnation. , constipation, abdominal pain and edema. It contains sennoside A, B, C, D, glucoside of chrysophanol, aloe-emodin and polysaccharide.
[ Main Functions ]
The active ingredient in senna is called sennoside. The constituent molecules are converted in the colon by microorganisms into another substance, anthrone rhein, which possesses beneficial effects to stimulate colonic activity (which accelerates bowel movements and improves digestion) and increases fluid secretion. The laxative effect of sennoside and its active metabolite, anthrone rhein, are thought to inhibit the absorption of water and electrolytes in the large intestine, thereby increasing the volume and pressure of intestinal contents. A push-pull tightening exercise that will stimulate the colon.
In addition, stimulation of active chloride secretion increased intestinal water and electrolyte content. These changes in active electrolyte transport depend on the elemental calcium on the serosal surface. The laxative effect of sennoside is in part through stimulation of colonic fluid and electrolyte secretion, and this secretory capacity is mediated by stimulation of endogenous prostaglandin formation. Pudose can be prepared as an enema or suppository or mixed with a stool softener or bulk fiber laxative to form a combined laxative.
------------------------------ Certificate of Analysis-----------------------------
| CERTIFICATE OF ANALYSIS | |||
| Product and Batch Information | |||
| Product Name: | Senna Extract | Country of Origin: | P. R. China |
| Botanic Name: | Senna alexandrina Mill. | Batch No.: | 20220527 |
| Part Used: | Leaf | Manufacture Date: | 2022-05-27 |
| Solvent Used: | Ethanol & Water | Analysis Date: | 2022-05-27 |
| Ananlysis: | 200kg | ||
| Analysis Item | Specification | Result | Test Method |
| Active Ingredeints | |||
| Sennosides (A+B) | NLT8% | 8.18% | HPLC |
| Physical Control | |||
| Identification | Positive | Complies | TLC |
| Appearance | Brown yellow powder | Complies | Visual |
| Odor | Characteristic | Complies | Organoleptic |
| Taste | Characteristic | Complies | Organoleptic |
| Sieve Analysis | 100% pass 80 mesh | Complies | 80 Mesh Screen |
| Loss on Drying | 5% Max | 2.68% | 5g/105oC/5hrs |
| Ash | 5% Max | 2.98% | 2g/525oC/5hrs |
| Chemical Control | |||
| Arsenic (As) | NMT 2ppm | Complies | Atomic Absorption |
| Cadmium(Cd) | NMT1ppm | Complies | Atomic Absorption |
| Lead (Pb) | NMT3ppm | Complies | Atomic Absorption |
| Mercury(Hg) | NMT0.1ppm | Complies | Atomic Absorption |
| Heavy Metals | 10ppm Max | Complies | Atomic Absorption |
| Pesticides Residues | NMT 1ppm | Complies | Gas Chromatography |
| Microbiological Control | |||
| Total Plate Count | 10000cfu/g Max | Complies | CP2005 |
| P.aeruginosa | Negative | Complies | CP2005 |
| S. aureus | Negative | Complies | CP2005 |
| Salmonella | Negative | Complies | CP2005 |
| Yeast & Mold | 1000cfu/g Max | Complies | CP2005 |
| E.Coli | Negative | Negative | CP2005 |
| Packing and Storage | |||
| Packing | 25kg/drum Packing in paper-drums and two plastic-bags inside. | ||
| Storage | Store in a well-closed container away from moisture. | ||
| Shelf Life | 2 years if sealed and store away from direct sun light. | ||
| Expiration Date | 2024-05-26 | ||
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