Customization: | Available |
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Certification: | RoHS, BRC, ISO, FDA, HACCP |
Assay Method: | HPLC |
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[ Product Name ] Diosmin 9:1
[ Appearance ] A greyish-yellow to pale brown powder
[ Active Ingredients ] Diosmin 9:1
[ Shelf Life ] 2 years if sealed and store away from direct sun light.
[ Main Functions ]
A flavonoid found in citrus fruits and an agonist of the aryl hydrocarbon receptor (AhR).
Mechanism
1. Enhancing venous tension Diosmin enhances venous wall tension, even under high temperature. It causes a stronger venous contraction than other drugs such as rutin. It can still enhance venous tension when the body is in acidosis. . Diosmin has a specific affinity for veins without affecting the arterial system.
2. Improve microcirculation diosmin can significantly reduce the adhesion, migration, disintegration and release of inflammatory substances, such as histamine, bradykinin, complement, leukotrienes, prostaglandins and excessive Free radicals, etc., thereby reducing the permeability of capillaries and enhancing their tension, diosmin also has the function of reducing blood viscosity and enhancing the flow rate of red blood cells, thereby reducing microcirculation stasis.
3. Promote lymphatic return diosmin increases the speed of lymphatic drainage
------------------------------- Certificate of Analysis----------------------------
Items tested | Specifications | Method | |
appearance | A greyish-yellow to pale brown powder | Visual | |
Identification | Positive | HPLC | |
Solubility |
Practically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in alcohol it dissolves in dilute solutions of alkali hydroxides. | Visual | |
Iodine | ≤ 0.1% | ||
Substances |
Impurity A(Acetoisovanillone) | ≤1% | HPLC |
Impurity C(Isorhoifolin): | ≤3% | HPLC | |
Impurity E(Linarin): | ≤3% | HPLC | |
Impurity F(Diosmitin): | ≤3% | HPLC | |
Water | ≤6.0% | Eur.Ph.9.0 <2.4.16> | |
Sulphated Ash | ≤0.2% | Eur.Ph.9.0 <2.5.12> | |
Solvent Resides | ≤300ppm | GC | |
Particle size | 100% through 80mesh | USP39 <786> | |
Heavy metals | ≤20ppm | ||
Diosmin: | 81.0%~92.0% | HPLC | |
Hesperidin: | 9.0%~14.0% | HPLC | |
Microbiology | |||
Total bacteria count | ≤1000CFU/g | USP39 <61> | |
Yeasts and moulds | ≤100CFU/g | USP39 <61> | |
E.Coli | Negative | USP39 <62> | |
Salmonella | Negative/10g | USP39 <62> | |
Coliforms | ≤10CFU/g | USP39 <62> | |
Parking | Packed in Paper-drums and two plastic-bags inside. | ||
Storage | Store in cool & dry place. Do not freeze. Keep away from strong light and heat | ||
Shelf life | 2 years when properly stored |